Yes. Change the base URL that enables "deep" links to individual local catalog records listed in the WorldCat Registry > Online Catalog section of OCLC Service Configuration. Information entered there is used by WorldCat.org and FirstSearch. (The Services section of your Registry profile also lets you enter or update other links used in WorldCat.org results, such as your IP address or address range, "Ask a Librarian" virtual reference service, OpenURL resolver for full text access, and general Web information page listing hours, location, etc.)
Changes made to your library's OPAC and service links in the WorldCat Registry should be active within 24 hours.